Possess anti-oxidant effect as proved by DPPH and NO (nitric oxide) assays
|Verdura mela gain cream||IC 50 value at 10 mg/ml|
|Absorbic acid (positive control)||IC 50 value at 1.52 mg/ml|
Inhibits DPPH with IC 50 value of 10 mg/ml
INHIBITION OF NITRIC OXIDE (NO) PRODUCTION
|Test Details||% of Nitrate Production|
|Only LPS (Positive Control)||73|
|LPS + 50 mg of Verdura mela gain cream||38|
Inhibits the production of NO with IC 50 value of 40 mg/ml
Augments intracellular tyrosinase production and its activity.
Intracellular tyrosinase assay
B16F10 melanoma cells treated with Verdura mela gain cream showed increased tyrosinase activity.
Verdura mela gain cream is as effective as α-MSH (Positive control) in increasing melanogenesis.
Verdura mela gain cream proven to be safe, non-irritant and non cytotoxic.
Zein protein hydrolysis assay
Fibroblast toxicity test- MTT assay
Clinically proven to increase melanin production and sun protection
Dual active technology - Sun protection & Melanogenesis
Dual active technology is essential for vitiligo patients as their skin is vulnerable to sun damage.